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Fix: share LD partition across GWAS, readr namespace, susie robustness#436

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gaow merged 1 commit intoStatFunGen:mainfrom
kal26:fix/ld-shared-namespace-susie
Mar 4, 2026
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Fix: share LD partition across GWAS, readr namespace, susie robustness#436
gaow merged 1 commit intoStatFunGen:mainfrom
kal26:fix/ld-shared-namespace-susie

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@kal26 kal26 commented Mar 3, 2026

  • Pre-compute partition_LD_matrix once per LD block (shared across all GWAS) instead of recomputing for each study; avoids redundant processing
  • Use readr::col_* in load_genotype_region to avoid namespace conflicts
  • susie_rss_wrapper: handle NA in LD matrix, force symmetry, remap PIP/cs when variants are dropped

Made-with: Cursor

- Pre-compute partition_LD_matrix once per LD block (shared across all GWAS)
  instead of recomputing for each study; avoids redundant processing
- Use readr::col_* in load_genotype_region to avoid namespace conflicts
- susie_rss_wrapper: handle NA in LD matrix, force symmetry, remap PIP/cs
  when variants are dropped

Made-with: Cursor
@gaow gaow merged commit 9070ba7 into StatFunGen:main Mar 4, 2026
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2 participants